Self-Assembled Porphyrin Nanoparticles - Emerging Biomedical Applications
Abstract:
Porphyrins have played numerous historic roles in development of approaches to diagnosis and treat of diseases. This lecture will cover some of our own recent efforts to develop new self-assembled materials from porphyrins and related molecules, and how these nanomaterials might have potentially advantageous properties for disease diagnosis and therapy. In particular we will discuss several lines of research from our lab including 1) Light-triggered drug release from liposomes containing small amounts of porphyrin-phospholipids; 2) Seamless decoration of liposomes containing cobalt-porphyrin-phospholipid with his-tagged antigens; 3) High-density porphyrin nanostructures for biomedical contrast imaging. Bio:
Jonathan F. Lovell is an assistant Professor of Biomedical Engineering at the State University of New York at Buffalo. He received his Ph.D. in Biomedical Engineering from the University of Toronto in 2012 in the lab of Dr. Gang Zheng. He previously completed a MS degree at McMaster University with Dr. David Andrews. He is a 2013 recipient of the NIH Early Independence Award, a 2015 recipient of the Rita Schaffer Young Investigator Award of the Biomedical Engineering Society and a 2016 recipient of an NSF CAREER Award. His main research interests involve developing clinically translatable nanoplatforms for treating and preventing disease. Molecular Engineering and Sciences Seminar Series This weekly seminar brings together students, faculty and invited guests from various disciplines across campus to explore current trends in molecular engineering and nanotechnology. It is a forum for active interdisciplinary discussions. These talks are open to the public and attract a diverse audience of students and faculty. |