UW Pathology Presents “Whole Genome Sequencing for Clinical Cancer Diagnostics" Eric Duncavage, MD Professor Director Section of Hematopathology Director Section of Molecular Oncology Department of Pathology and Immunology Washington University in St. Louis Why Attend this Seminar? Cytogenetic evaluation of AML and MDS has been the mainstay of clinical risk assessment for over 40 years. While effective for risk-stratification, cytogenetics requires the culture of live cells and provides limited resolution to resolve complex genomic events. Whole genome sequencing, WGS, is capable of unbiased genomic evaluation from DNA but has been considered too expensive, too complicated, and too slow for clinical use. In this seminar we will discuss recent advances that have made WGS feasible in the clinical setting, how WGS data can be used for the comprehensive genomic assessment of AML and MDS patients, and how WGS could be implemented for the evaluation of other cancer types. Meeting ID: 922 0180 0473 Passcode: 520 |