Somatic evolution through the lens of single-cell multi-omics Dan Landau, MD, PhD Associate Professor of Medicine Weill Cornell Medicine & Core Member New York Genome Center Why Attend this Seminar? Somatic cells in our body undergo an evolutionary process throughout our lives; through mutagenesis and clonal selection. This phenomenon is ubiquitous in normal tissues with aging, associated with various disease states, and in its extreme form leads to malignancy – a runaway evolutionary process. In this seminar, we will review array of technologies developed to map somatic genotypes to a variety of phenotypes through single cell multi-omics, as well as chart the evolutionary dynamics of clonal outgrowths. Meeting ID: 930 4620 8772 Passcode: PATH520 |