Kathryn P. Scherpelz, MD, PhD Associate Director, Autopsy and After Death Services Acting Assistant Professor, Autopsy Pathology, Neuropathology, and Ophthalmology Department of Laboratory Medicine & Pathology University of Washington Objectives: - Explain the unique accessibility of the retina as part of the central nervous system.
- Describe at least three changes indicative of neurodegeneration in the retina.
- Compare neurodegenerative changes seen in the retina with those in the brain.
Speaker disclosures: Dr. Kathryn P. Scherpelz has NOT had any financial relationships with any ineligible entities within the past 24 months. Why Attend? Neurodegenerative disease imposes a large burden on patients, caregivers, and society. Multiple forms of neurodegenerative disease have been defined based on postmortem histopathologic findings in the brain. Although clinical evaluations and modern imaging contribute to the classification of neurodegenerative diseases, these methods can produce errors and premortem diagnosis remains challenging. The retina is a component of the central nervous system which is uniquely accessible premortem. Retinal features which correlate with neurodegenerative disease may allow more accurate diagnosis of neurodegeneration during life, as well as providing a means to measure disease progression or therapeutic response over time. Identifying such retinal features is an active area of research. This talk will discuss findings in postmortem retinas from brain donors with and without neurodegenerative disease, and similarities and differences between retinal and cerebral histologic changes associated with aging and neurodegeneration. Meeting ID: 983 8715 9855 Passcode: PATHGR You must sign-in on the following form to receive CME credit. Sign-in online: https://forms.gle/W2oE8d3MYbnyTDe58
Planning Committee Disclosure: The following members have not had any financial relationships with any ineligible entities in the past 24 months: Drs. Rebecca Alvarez, Eleanor Chen, Austin Green, Jose Mantilla, Isaac Miller, Elizabeth Parker, Maria Tretiakova, and Larry True. The following members disclose financial relations with ineligible entities within the past 24 months: Dr Shreeram Akilesh GoldfinchBio, Inc. (sponsored research) and NanoString, Inc. (sponsored travel); and Dr. Haodong Xu PathomIQ (consultant). All relevant financial relationships listed have been mitigated.
Grant Acknowledgment: None
CME Accreditation statement: The University of Washington School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The University of Washington School of Medicine designates this live activity for a maximum of 10.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. (Each session is 1.0 credit) |