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Marco Di Antonio, Imperial College

Biological Chemistry Seminar at the University of Utah TBBC 4630 (4th floor Thatcher) Long-range G-G base pairing regulates chromatin architecture and promotes RNA condensation in neurodegenerative diseases by Marco Di Antonio, Imperial College Abstract: It is well known that the Guanine base can base pair with itself by means of Hoogsteen hydrogen bonding, which can lead to the formation of DNA and RNA secondary structures known as G-quadruplex (G4).1 Whilst G4-formation has been thoroughly investigated within short genomic sequences, G-G base pairing between distal genomic regions have been often overlooked and deemed unlikely to happen in vivo. We have recently discovered the first human protein (CSB), a chromatin remodelling protein, that can selectively bind to multimolecular G4-structures (mG4s), suggesting that long range G-G base pairing can be potentially leveraged to orchestrate chromatin architecture.2 Using genome-wide mapping strategies to underpin G4-formation in human chromatin, we have… Event Categories: Seminars. Campus Locations: Thatcher Chemistry Building (TBBC). Contact Name: Amy Beardshall. Contact Phone: 8015816681. Contact Email: amy.beardshall@utah.edu. Campus Wide Event: Yes. Tuesday, April 2, 2024, 10:45 AM – 12:00 PM.

Jeffrey Rudolf, University of Florida

Biological Chemistry Seminar at the University of Utah TBBC 4630 (4th floor Thatcher) Exploring the Bacterial Terpenome by Jeffrey Rudolf, University of Florida Abstract: Terpenoids are the largest and most structurally diverse family of natural products and are a rich reservoir of pharmaceuticals, vitamins, flavors, fragrances, and biofuels. There are over 90,000 known terpenoids but less than 2% of these (≅1500) are of bacterial origin. Genomics, however, supports vast untapped biosynthetic potential for terpenoids in bacteria. Here, we summarize some of our recent work on genome mining for bacterial terpenoids and the enzymes that create these structurally complex small molecules. Host: Aaron Puri. Event Categories: Seminars. Campus Locations: Thatcher Chemistry Building (TBBC). Campus Wide Event: Yes. Thursday, April 4, 2024, 10:45 AM – 12:00 PM.

Distinguished Faculty Lecture with Michael Morse, University of Utah

Distinguished Faculty Lecture with Michael Morse, University of Utah TBBC 4630 4th Floor Thatcher Title: TBA with Michael Morse, Distinguished Professor with University of Utah Abstract: TBA Host: Matt Sigman. Event Categories: Seminars. Campus Locations: Thatcher Chemistry Building (TBBC). Contact Name: Amy Beardshall. Contact Phone: 8015816681. Contact Email: amy.beardshall@utah.edu. Campus Wide Event: Yes. Monday, April 8, 2024, 4:00 PM – 5:00 PM.

Stephanie Felton, Abbvie, Canter of Catalysis

Organic Chemistry Seminar at the University of Utah TBBC 4630 (4th floor Thatcher) Title: TBA by Stephanie Felton, Abbvie, Center of Catalysis Abstract: TBA Host: Andrew Roberts. Event Categories: Seminars. Campus Wide Event: Yes. Thursday, April 11, 2024, 10:45 AM – 12:00 PM.

Curie Club and ChemSAC Coffee Chat

Event Categories: Seminars. Campus Locations: Eyring Chemistry Building - Henry (HEB). Contact Name: Amy Beardshall. Contact Phone: 8015816681. Contact Email: amy.beardshall@utah.edu. Campus Wide Event: Yes. Tuesday, April 16, 2024, 12:00 PM – 1:30 PM.

Bram Axelrod, Purdue University

Organic Chemistry Seminar at the University of Utah TBBC 4630 (4th floor Thatcher) Title: TBA by Bram Axelrod, Purdue University  Abstract: TBA Host: Andrew Roberts. Event Categories: Seminars. Campus Locations: Thatcher Chemistry Building (TBBC). Campus Wide Event: Yes. Thursday, April 18, 2024, 10:45 AM – 12:00 PM.

Lance Seefeldt, Utah State University

Inorganic and Biological Chemistry Seminar at the University of Utah TBBC 4630 (4th floor Thatcher) Insights into the Nitrogenase Mechanism by Lance Seefeldt, Utah State University Abstract: Nitrogenase catalyzes the reduction of N2 to NH3, a central reaction in the global N cycle.  We will review the latest insights into the mechanism of N2 binding and reduction at the active site metal cofactors.   Host: Ming Lee Tang. Event Categories: Seminars. Campus Locations: Thatcher Chemistry Building (TBBC). Contact Name: Amy Beardshall. Contact Phone: 8015816681. Contact Email: amy.beardshall@utah.edu. Campus Wide Event: Yes. Tuesday, April 23, 2024, 10:45 AM – 12:00 PM.

Recursion Seminar with Abigail Doyle, UCLA

The Recursion Seminar at the University of Utah with Abigail Doyle, UCLA TBBC 4630 (4th floor Thatcher) Title: TBA by Abigail Doyle, UCLA Abstract: TBA Host: Matt Sigman. Event Categories: Seminars. Campus Locations: Thatcher Chemistry Building (TBBC). Contact Name: Amy Beardshall. Contact Phone: 8015816681. Contact Email: amy.beardshall@utah.edu. Campus Wide Event: Yes. Thursday, April 25, 2024, 10:45 AM – 12:00 PM.

Gabriela Schlau-Cohen, MIT

Physical Chemistry Seminar at the University of Utah TBBC 4630 (4th floor Thatcher) Title: TBA by Gabriela Schlau-Cohen, MIT Abstract: TBA Host: Rodrigo Noriega. Event Categories: Seminars. Campus Locations: Thatcher Chemistry Building (TBBC). Campus Wide Event: Yes. Monday, April 29, 2024, 4:00 PM – 5:00 PM.

Ahmed Hamid, Auburn University

Analytical Chemistry Seminar at the University of Utah TBBC 4630 (4th floor Thatcher) Title: TBA by Ahmed Hamid, Auburn University Abstract: TBA Host: Gabe Nagy. Event Categories: Seminars. Campus Locations: Thatcher Chemistry Building (TBBC). Contact Name: Amy Beardshall. Contact Phone: 8015816681. Contact Email: amy.beardshall@utah.edu. Campus Wide Event: Yes. Monday, May 6, 2024, 4:00 PM – 5:00 PM.

Justin Kim, Dana-Garber Cancer Institute

Organic Chemistry Seminar at the University of Utah TBBC 4630 (4th floor Thatcher) Title: TBA by Justin Kim, Dana-Farber Cancer Institute Abstract: TBA Host: Andrew Roberts. Event Categories: Seminars. Campus Locations: Thatcher Chemistry Building (TBBC). Contact Name: Amy Beardshall. Contact Phone: 8015816681. Contact Email: amy.beardshall@utah.edu. Campus Wide Event: Yes. Thursday, May 9, 2024, 10:45 AM – 12:00 PM.

The Novartis Chemical Sciences Lectureships with Sarah Reisman, Caltech

The Novartis Chemical Sciences Lectureships at the University of Utah with Sarah Reisman, Caltech TBBC 4630 (4th floor Thatcher) Title: TBA by Sarah Reisman, Caltech Abstract: TBA Host: Matt Sigman. Event Categories: Seminars. Campus Locations: Thatcher Chemistry Building (TBBC). Contact Name: Amy Beardshall. Contact Phone: 8015816681. Contact Email: amy.beardshall@utah.edu. Campus Wide Event: Yes. Thursday, May 16, 2024, 10:45 AM – 12:00 PM.

They Henry Eyring Theory Lecture with Victor Batista, Yale

The Henry Eyring Theory Lecture at the University of Utah with Victor Batista, Yale TBBC 4630 (4th floor Thatcher) Studies of Natural and Artificial Photosynthesis by Victor Batista, Yale Abstract: Mechanistic investigations of the water-splitting reaction are fundamentally informed by structural studies of the oxygen-evolving complex (OEC) of photosystem II (PSII) and biomimetic catalytic complexes. Many physical techniques have provided important insights into the OEC structure and function, including X-ray diffraction (XRD) and extended X-ray absorption fine structure (EXAFS) spectroscopy as well as mass spectrometry (MS), electron paramagnetic resonance (EPR) spectroscopy, and Fourier transform infrared spectroscopy applied in conjunction with mutagenesis studies. However, experimental studies have yet to yield consensus as to the nature of the reaction mechanism responsible for oxygen evolution. Computational modeling studies, including density functional (DFT) theory combined with quantum mechanics/mo… Event Categories: Seminars. Campus Locations: Thatcher Chemistry Building (TBBC). Campus Wide Event: Yes. Monday, May 20, 2024, 4:00 PM – 5:00 PM.

Curie Club and ChemSAC Coffee Chat

. Event Categories: Seminars. Campus Locations: Eyring Chemistry Building - Henry (HEB). Contact Name: Amy Beardshall. Contact Phone: 8015816681. Contact Email: amy.beardshall@utah.edu. Campus Wide Event: Yes. Tuesday, May 21, 2024, 10:00 AM – 11:30 AM.