NAPE presents: Dr. Michael Krashes (NIDDK)
NAPE CENTER SEMINAR SERIES:
Date: Fri, Oct 2, 2026
Time: 11:00 - 12:00pm
Location: HSB T435
Speaker: Dr. Michael Krashes, Senior Investigator NIDDK
Talk Title: Semaglutide drives weight loss through cAMP-dependent mechanisms in GLP1R-expressing hindbrain neurons
Glucagon-like peptide 1 receptor (GLP1R) agonists, such as semaglutide, drive weight loss by binding to GLP1Rs-classically described as Gs-coupled G-protein-coupled receptors-in the brain; however, the intracellular signalling mechanisms underlying these effects remain poorly defined. Here, we find that semaglutide engages both Gs- and Gq-dependent signalling pathways in Glp1r-expressing neurons in the area postrema (APGlp1r), the primary site of semaglutide action in the brain, and differentially regulates neuronal activation across distinct neuronal clusters. Semaglutide also drives graded increases of the essential secondary messenger cyclic adenosine monophosphate (cAMP) in APGlp1r neurons through the Gs pathway. Inhibition of the…
Event interval: Single day event. Campus location: Magnuson Health Sciences Center T (HST). Campus room: T-435. Accessibility Contact: Please contact Lydia Gordon-Fennell at lgordonf@uw.edu if accommodations are required. Event Types: Academics. Lectures/Seminars.
Friday, October 2, 2026, 11:00 AM – 12:00 PM.
Neuro 510: Coffee & Connections (AUT 2026)
Members of the Neuroscience community and the public are welcome to join us for the first Neuro 510 seminar of Autumn Quarter.
Neuroscience PhD students, Elena Judd (Labs of Michael Bruchas & Richard Palmiter) and Christina Wang (Labs of Matt Golub & Kayvon Daie) will present on their research.
NOTE ROOM CHANGE to HST T-369. .
Event interval: Single day event. Campus location: Magnuson Health Sciences Center T (HST). Campus room: T-369. Accessibility Contact: Please contact Jennifer Simpson at neurogrd@uw.edu if accommodations are required. Event Types: Academics. Lectures/Seminars.
Monday, October 5, 2026, 3:30 PM – 4:20 PM.
Neuroscience PhD Info Session (3 of 3)
This session is for prospective applicants interested in joining the UW Neuroscience Autumn 2027 cohort. We will discuss questions related to the 2027 application process along with any other questions applicants may have about the program or life in Seattle.
Event interval: Single day event. Online Meeting Link: https://washington.zoom.us/j/91662328733. Accessibility Contact: Please contact Jennifer Simpson at neurogrd@uw.edu if accommodations are required. Event Types: Academics. Information Sessions.
Thursday, October 15, 2026, 12:00 PM – 1:00 PM.
Zoom.
Art Neureau 2026
The UW Graduate Program in Neuroscience and the Eberhard Fetz Art Fund Presents:
Art Neureau 2026
Thursday, October 29th 6-9 p.m.
Fremont Abbey
There will be Neuroscience-themed art, food, live music, and merchandise.
Suggested $5 donation by cash or Venmo.
Event interval: Single day event. Accessibility Contact: Please contact Jennifer Simpson at neurogrd@uw.edu if accommodations are required. Event Types: Exhibits.
Thursday, October 29, 2026, 6:00 PM – 9:00 PM.
https://maps.app.goo.gl/ZfXQgVY59z3PrFsT7.
2027 Neuro PhD Applications Close
Event interval: Single day event. Accessibility Contact: Please contact Jennifer Simpson at neurogrd@uw.edu if accommodations are required. Event Types: Academics.
Thursday, November 12, 2026, 11:58 PM – 11:59 PM.
For more info visit gpneuro.uw.edu. ABRCMS 2026: Seattle Convention Center
The Graduate Program in Neuroscience will be attending ABRCMS 2026 in the Seattle Convention Center.
Registration is open.
Event interval: Ongoing event. Accessibility Contact: This event is hosted by ABRCMS. Please contact abrcms@asmusa.org for accessibility assistance. Event Types: Information Sessions. Exhibits.
Wednesday, November 18, 2026 – Friday, November 20, 2026.
https://maps.app.goo.gl/iiR94WpHJ6wMzVJ96.
For more info visit abrcms.org. Neuro 510: Be Boundless (AUT2026)
Join us for Be Boundless, our final Neuro 510 seminar of Autumn Quarter, to hear two post-docs present on their research! (Speakers to be announced.)
NOTE ROOM CHANGE to HST T-369. .
Event interval: Single day event. Campus location: Magnuson Health Sciences Center T (HST). Campus room: T-369 (Room updated). Accessibility Contact: Please contact Jennifer Simpson at neurogrd@uw.edu if accommodations are required. Event Types: Academics. Lectures/Seminars.
Monday, December 7, 2026, 3:30 PM – 4:20 PM.
Neuro First Years Rotation Talks (AUT26)
The 2026 Neuro Cohort will present ten-minute talks about their research in their Autumn lab rotations. Members of the Neuroscience community are welcome to attend and ask questions.
Event interval: Single day event. Campus location: Magnuson Health Sciences Center G (HSG). Campus room: G-328. Accessibility Contact: Please contact Jennifer Simpson at neurogrd@uw.edu if accommodations are required. Event Types: Academics. Lectures/Seminars.
Friday, December 18, 2026, 2:00 PM – 4:00 PM.