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SHACS: Litao Tao, PhD - Distal regulatory elements in inner ear development and deafness

Transcription enhancers are essential for dynamic expression regulation during development, and mutations in those distal elements can lead to diseases, including hereditary hearing loss. Due to the nature of distal elements and the paucity of cells in the inner ear, most enhancers driving cell type specific transcription in the inner ear have not yet been identified, let alone their regulatory functions. Leveraging new epigenetic analyzing techniques such as ATACseq, Cut&Run and Micro-C, we are able to overcome some of the barriers to profile the epigenomes and characterize distal enhancers in the inner ear. In this seminar, I will discuss our previous work on the role of enhancers in activating hair cell gene expression during differentiation and the epigenetic silencing mechanism underlying the loss of regeneration potential in surrounding supporting cells, as well as our current effort to annotate enhancers in the cochlea.   Litao Tao, PhD is an Assistant Professor of Biomedical Sciences at the… Event interval: Single day event. Campus location: Haring Center (IHDD). Campus room: Room CD150. Accessibility Contact: lfoy@uw.edu. Event Types: Academics. Lectures/Seminars. Target Audience: Faculty, students, researchers, lab members. Thursday, November 13, 2025, 2:30 PM – 3:30 PM.

Dissertation Defense - Kathryn Powers, "EBF1 Regulates Sensory Development in the Mammalian Cochlea"

Molecular & Cellular Biology in Seattle, an interdisciplinary PhD program offered through University of Washington and Fred Hutch invites you to the dissertation defense by Kathryn Powers from Olivia Bermingham-McDonogh's lab on Friday, November 21st at 1:30 pm. It will be held in UW Health Sciences Building T639. Her dissertation is entitled “EBF1 Regulates Sensory Development in the Mammalian Cochlea.” This event will also be presented virtually - please email mcb@uw.edu for the streaming link. Event interval: Single day event. Campus location: Magnuson Health Sciences Center B (HSB). Campus room: T639. Accessibility Contact: mcb@uw.edu. Event Types: Academics. Target Audience: Students, faculty, researchers, lab staff. Friday, November 21, 2025, 1:30 PM – 2:30 PM.

SHACS: Gavriel D. Kohlberg, MD

Associate Professor of Otolaryngology-HNS at University of Washington   The 2025-2026 SHACS lectures will all be held in person, and are free and open to the public. Event interval: Single day event. Campus location: Haring Center (IHDD). Campus room: Room CD150. Accessibility Contact: lfoy@uw.edu. Event Types: Academics. Lectures/Seminars. Target Audience: Faculty, students, researchers, lab members. Thursday, January 15, 2026, 2:30 PM – 3:30 PM.

SHACS: Debarshi Mustafi, MD, PhD

Assistant Professor of Ophthalmology at University of Washington   The 2025-2026 SHACS lectures will all be held in person, and are free and open to the public. Event interval: Single day event. Campus location: Haring Center (IHDD). Campus room: Room CD150. Accessibility Contact: lfoy@uw.edu. Event Types: Academics. Lectures/Seminars. Target Audience: Faculty, students, researchers, lab members. Thursday, January 29, 2026, 2:30 PM – 3:30 PM.

SHACS: Shuyi Ma, PhD - In vivo screening for ototoxicity-modulating drug interactions identifies antagonism that protects against hair cell damage

Assistant Professor of Pediatrics at University of Washington   The 2025-2026 SHACS lectures will all be held in person, and are free and open to the public. Event interval: Single day event. Campus location: Haring Center (IHDD). Campus room: Room CD150. Accessibility Contact: lfoy@uw.edu. Event Types: Academics. Lectures/Seminars. Target Audience: Faculty, students, researchers, lab members. Thursday, February 5, 2026, 2:30 PM – 3:30 PM.