Department of Chemistry

organic, chemistry, prof

Seattle, Washington — Pacific Time

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Labor Day

Administrative No classes. Most University offices and buildings are closed. Check with specific offices to confirm. Event interval: Single day event. Year: 2025. Quarter: Autumn. Event Types: Academics. Monday, September 1, 2025. For more info visit www.washington.edu.

Organic Chemistry Seminar: Prof. Matt Golder

Organic Seminars "TBA" Assistant Professor Matthew Golder - Department of Chemistry, University of Washington Host. Event interval: Single day event. Accessibility Contact: chem59x@uw.edu. Event Types: Lectures/Seminars. Thursday, September 25, 2025, 10:30 AM – 11:30 AM. For more info visit chem.washington.edu.

Hyp J. Dauben, Jr. Endowed Lecture in Organic Chemistry: Prof. Wilfred van der Donk

Organic Seminars Hyp J. Dauben, Jr. Endowed Lecture in Organic Chemistry "Genome Mining for New Chemistry" Professor Wilfred A. van der Donk - Department of Chemistry and Howard Hughes Medical Institute, University of Illinois Urbana-Champaign Host: Lauren Rajakovich The genome sequencing efforts of the past 20 years have revealed that ribosomally synthesized and post-translationally modified peptides (RiPPs) constitute a large class of peptide natural products. These molecules are produced in all three domains of life, their biosynthetic genes are ubiquitous in the currently sequenced genomes, and their structural diversity is vast. Furthermore, they are increasingly recognized for their involvement in fighting or causing human disease. This lecture will discuss the use of genome mining and synthetic biology for the discovery of new RiPPs that has also proven to be an excellent platform to discover new chemistry involved in their biosynthesis.1-3 (1) Nguyen, D. T.; Mitchell, D. A.; van der Donk, W. A. Genome mining for new… Event interval: Single day event. Campus room: TBD. Accessibility Contact: chem59x@uw.edu. Event Types: Lectures/Seminars. Event sponsors: This lecture is supported by the Hyp J. Dauben, Jr. Memorial Fund, established in memory of Prof. Dauben by his family, friends, colleagues, and students in 1968. Hyp J. Dauben, Jr. received bachelor’s and master’s degrees from the Ohio State University and his Ph.D. from Harvard University. He joined the Department of Chemistry at the University of Washington in 1945, and until his death in 1968, he played a major role in the development of the Department’s research facilities. Professor Dauben was intern… Wednesday, October 22, 2025, 4:00 PM – 5:00 PM. For more info visit www.vanderdonk.scs.illinois.edu.

Organic Chemistry Seminar: Prof. Wilfred van der Donk

Organic Seminars "Biosynthesis and Engineering of Macrocyclic Peptides" Professor Wilfred A. van der Donk - Department of Chemistry and Howard Hughes Medical Institute, University of Illinois Urbana-Champaign Host: Lauren Rajakovich Ribosomally synthesized and post-translationally modified peptides (RiPPs) constitute a very large class of peptide natural products. Lanthionine-containing peptides are examples of this rapidly growing class. These peptides are post-translationally modified to install multiple thioether crosslinks. During their biosynthesis, a single enzyme typically breaks 8-16 chemical bonds and forms 6-10 new bonds with high control over site- and chemoselectivity. This lecture will discuss utilization of these biocatalysts for bioengineering purposes and generation and use of macrocyclic peptide libraries. The lecture will also present mechanistic insights into the remarkable biocatalysts that transform a linear peptide into polycyclic products. Event interval: Single day event. Campus room: TBD. Accessibility Contact: chem59x@uw.edu. Event Types: Lectures/Seminars. Thursday, October 23, 2025, 10:30 AM – 11:30 AM. For more info visit www.vanderdonk.scs.illinois.edu.